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德戈氏病的超微结构研究(一例新病例报告及文献综述)(作者译)

[Ultrastructural study of the Dego's disease (report of a new case and literature review) (author's transl)].

作者信息

Olmos L, Laugier P

出版信息

Ann Dermatol Venereol. 1977 Apr;104(4):280-93.

PMID:889231
Abstract

An observation of a new case of Degos' disease in a 42 year old woman presenting a merely cutaneous symptomatology, enabled to perform a detailed ultrastructural study of vascular lesions, nerves, infiltrate and perivascular fibroblasts. The episodic clinical evolution with various formation periods of vascular lesions, the frequency of virus-like inclusions in the endothelial cells and fibroblasts, as well as C3 deposits and the presence of intracytoplasmic cylinders in the histiocytes, suggest a common physiopathologic mechanism with the autoimmune diseases. A bibliographic review accompanies the clinico-pathological study.

摘要

对一名42岁仅表现为皮肤症状的德戈斯病新病例的观察,使得能够对血管病变、神经、浸润及血管周围成纤维细胞进行详细的超微结构研究。血管病变形成期各异的发作性临床演变、内皮细胞和成纤维细胞中病毒样包涵体的出现频率,以及补体C3沉积和组织细胞中胞质内圆柱体的存在,提示其与自身免疫性疾病存在共同的病理生理机制。临床病理研究附有文献综述。

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