Olmos L, Laugier P
Ann Dermatol Venereol. 1977 Apr;104(4):280-93.
An observation of a new case of Degos' disease in a 42 year old woman presenting a merely cutaneous symptomatology, enabled to perform a detailed ultrastructural study of vascular lesions, nerves, infiltrate and perivascular fibroblasts. The episodic clinical evolution with various formation periods of vascular lesions, the frequency of virus-like inclusions in the endothelial cells and fibroblasts, as well as C3 deposits and the presence of intracytoplasmic cylinders in the histiocytes, suggest a common physiopathologic mechanism with the autoimmune diseases. A bibliographic review accompanies the clinico-pathological study.
对一名42岁仅表现为皮肤症状的德戈斯病新病例的观察，使得能够对血管病变、神经、浸润及血管周围成纤维细胞进行详细的超微结构研究。血管病变形成期各异的发作性临床演变、内皮细胞和成纤维细胞中病毒样包涵体的出现频率，以及补体C3沉积和组织细胞中胞质内圆柱体的存在，提示其与自身免疫性疾病存在共同的病理生理机制。临床病理研究附有文献综述。
