Daftari T K, Levine J, Fischgrund J S, Herkowitz H N
Georgia Orthopaedics Sports Medicine, Austell, USA.
Spine (Phila Pa 1976). 1996 Sep 15;21(18):2156-9. doi: 10.1097/00007632-199609150-00019.
A retrospective chart review was performed from 1990-1994.
To evaluate the outcome of pathologic examination of cervical disc specimens submitted after anterior cervical discectomy.
This study is the first to review the outcome of pathologic examination of disc specimens after anterior cervical discectomy and fusion.
Charts were reviewed based on the procedure code of anterior cervical fusion and the main diagnoses of cervical disc and spondylosis. The following data were recorded for each patient: symptoms, examination, diagnostic studies, operative procedure, operative findings, and pathology report. Statistical analysis was performed.
Five hundred six disc levels in 394 patients were reviewed. All patients had symptoms and examination results consistent with cervical radiculopathy. All patients had cervical radiographs and some combination of myelography, computed tomography, or magnetic resonance imaging. Findings at the time of surgery included the presence of either a herniated disc or degenerative spondylitic changes. The pathologic examination results of all specimens reported fibrocartilaginous tissue consistent with disc material with the presence of degenerative changes. No infectious, benign, or malignant process was identified at the time of surgery or on gross and histologic examination of any of the disc specimens. Using confidence intervals (95%) for exact proportions and given 500 negatives, the chance the next occurrence would be positive would be 0.0060 or 0.60% or six of 1000.
This study shows that if the symptoms, physical examination, radiographic diagnostic studies, and surgical findings are consistent with those of cervical disc herniation of spondylosis, the chance of an unexpected, clinically important pathologic finding within the disc specimen is extremely small. The time and expense involved in routine pathologic examination of cervical disc specimens can be avoided.
对1990年至1994年的病历进行回顾性分析。
评估颈椎前路椎间盘切除术后提交的颈椎间盘标本的病理检查结果。
本研究首次回顾了颈椎前路椎间盘切除融合术后椎间盘标本的病理检查结果。
根据颈椎前路融合手术编码以及颈椎间盘和颈椎病的主要诊断对病历进行回顾。记录每位患者的以下数据:症状、检查、诊断性研究、手术过程、手术发现和病理报告。进行了统计分析。
对394例患者的506个椎间盘节段进行了回顾。所有患者的症状和检查结果均与神经根型颈椎病相符。所有患者均进行了颈椎X线检查,部分患者还进行了脊髓造影、计算机断层扫描或磁共振成像检查。手术时的发现包括椎间盘突出或退行性脊柱病变。所有标本的病理检查结果均报告为与椎间盘组织相符的纤维软骨组织,并伴有退行性改变。在手术时或对任何椎间盘标本进行大体和组织学检查时,均未发现感染、良性或恶性病变。使用精确比例的95%置信区间,并假设有500个阴性结果,下一次出现阳性结果的概率为0.0060或0.60%,即千分之六。
本研究表明,如果症状、体格检查、影像学诊断研究和手术发现与颈椎病椎间盘突出相符,椎间盘标本中出现意外的、具有临床重要意义的病理发现的可能性极小。可以避免对颈椎间盘标本进行常规病理检查所涉及的时间和费用。