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聚甲基丙烯酸甲酯椎体间融合术治疗颈椎间盘疾病的前路椎间盘切除术:249例患者的长期结果

Ventral discectomy with pmma interbody fusion for cervical disc disease: long-term results in 249 patients.

作者信息

Hamburger C, Festenberg F V, Uhl E

机构信息

and the Department of Neurosurgery, Grosshadern University Hospital, Ludwig-Maximilians-University, Munich, Germany.

出版信息

Spine (Phila Pa 1976). 2001 Feb 1;26(3):249-55. doi: 10.1097/00007632-200102010-00009.

Abstract

STUDY DESIGN

Retrospective study of patients who underwent ventral discectomy and polymethyl-methacrylate (PMMA) interbody fusion for cervical radiculopathy.

OBJECTIVES

To evaluate the long-term outcome after ventral discectomy and PMMA interbody fusion and to compare it with previous data from other surgical techniques for the treatment of cervical radiculopathy.

SUMMARY OF BACKGROUND DATA

Because PMMA interbody fusion after ventral discectomy does not result in solid bony fusion in all cases, a good long-term outcome using this surgical technique has been questioned.

METHODS

Long-term follow-up evaluation after surgery was performed in 249 patients (96 women and 153 men) with radicular signs only. The mean age was 46.0 +/- 8.7 years (range, 24-74 years), and the observation time ranged from 10-15 years (mean, 12.2 +/- 1.2 years). Clinical grading after surgery according to Odom's criteria was based on a questionnaire. The outcome was related to morphologic findings, lumbar symptoms, physical stress, duration of symptoms, age, sex, and cervical level involved.

RESULTS

Complications related to surgery occurred in 13 (5.2%) patients, but only three (1.2%) had persistent problems. Of the 249 patients, 101 (40.6%) were without any symptoms (Odom I), 92 (36.9%) had a good outcome (Odom II), and 47 (18.9%) a fair outcome (Odom III). Only nine patients (3.6%) reported an unchanged or worse status than before surgery (Odom IV). Additional lumbar symptoms, high occupational physical stress, and discrepancy of preoperative findings were significantly correlated with a worse outcome. Short duration of symptoms and soft disc disease were favorable prognostic factors.

CONCLUSIONS

PMMA interbody fusion after ventral discectomy in cervical disc surgery is a safe and reliable method with few complications and an outcome comparable with other ventral procedures.

摘要

研究设计

对因颈椎神经根病接受前路椎间盘切除术和聚甲基丙烯酸甲酯(PMMA)椎间融合术的患者进行回顾性研究。

目的

评估前路椎间盘切除术和PMMA椎间融合术后的长期疗效,并与先前其他治疗颈椎神经根病的手术技术的数据进行比较。

背景资料总结

由于前路椎间盘切除术后的PMMA椎间融合术并非在所有病例中都能实现牢固的骨融合,因此这种手术技术能否带来良好的长期疗效受到了质疑。

方法

对仅出现神经根症状的249例患者(96例女性和153例男性)进行术后长期随访评估。平均年龄为46.0±8.7岁(范围24 - 74岁),观察时间为10 - 15年(平均12.2±1.2年)。术后根据奥多姆标准进行的临床分级基于一份调查问卷。疗效与形态学表现、腰部症状、身体应激、症状持续时间、年龄、性别以及受累颈椎节段相关。

结果

13例(5.2%)患者出现与手术相关的并发症,但只有3例(1.2%)存在持续性问题。在249例患者中,101例(40.6%)无症状(奥多姆I级),92例(36.9%)疗效良好(奥多姆II级),47例(18.9%)疗效尚可(奥多姆III级)。只有9例患者(3.6%)报告病情未改善或比手术前更差(奥多姆IV级)。额外的腰部症状、高职业身体应激以及术前检查结果不一致与较差的疗效显著相关。症状持续时间短和软性椎间盘疾病是有利的预后因素。

结论

颈椎间盘手术中,前路椎间盘切除术后的PMMA椎间融合术是一种安全可靠的方法,并发症少,疗效与其他前路手术相当。

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