Bhambhani Y, Burnham R, Snydmiller G, MacLean I, Lovlin R
Department of Rehabilitation Medicine, University of Alberta, Edmonton, Canada.
J Occup Environ Med. 1996 Oct;38(10):1012-7. doi: 10.1097/00043764-199610000-00011.
This study examined the acute effects of oral inhalation of 10-ppm hydrogen sulfide (H2S) inhalation (a concentration equal to its occupational exposure limit) on the pulmonary function in healthy men and women. Nine men and ten women consented to inhale medical air or 10 ppm H2S for 15 minutes each during cycle exercise at 50% of their maximal aerobic power. Routine pulmonary function tests were administered at rest and immediately after the two exposure conditions. The results indicated no significant changes in any of the variables derived from the flow volume loop, maximum ventilation volume, and diffusion capacity of the lung for carbon monoxide in both genders. None of the subjects experienced any signs and symptoms as a result of H2S exposure. It was concluded that oral inhalation of 10 ppm H2S at an elevated metabolic and ventilation rate does not significantly alter pulmonary function in healthy men and women.
本研究检测了健康男性和女性经口吸入10 ppm硫化氢（H₂S）（浓度等于其职业接触限值）对肺功能的急性影响。9名男性和10名女性同意在以其最大有氧能力的50%进行自行车运动期间，分别吸入医用空气或10 ppm H₂S，每次15分钟。在静息状态以及两种暴露条件结束后立即进行常规肺功能测试。结果表明，两性在流量容积环、最大通气量和肺一氧化碳弥散量等指标上均未出现显著变化。所有受试者均未因H₂S暴露出现任何体征和症状。研究得出结论，在代谢和通气率升高的情况下，健康男性和女性经口吸入10 ppm H₂S不会显著改变肺功能。
