Antoine J M, André T, Antoine M, Lotz J P, Salat-Baroux J
Service de Gynécologie-obstétrique, Hpital Tenon, Paris.
J Gynecol Obstet Biol Reprod (Paris). 1996;25(1):53-5.
A case of mulleroblastoma, a malignant mixed Muller tumour, of the uterine body was observed in a 51-year-old patient. This is a rare but severe tumour. Clinically, there is a long latence period and early haematogenous metastases leading to failure of radiotherapy and surgical treatment. Recent data, particularly from immunohistochemistry studies, would suggest that the epithelial component plays a major role in pathogenesis. A therapeutic approach combining surgery, aggressive chemotherapy and radiotherapy allows improved prognosis.
