结合疫苗与b型流感嗜血杆菌携带情况
Conjugate vaccines and the carriage of Haemophilus influenzae type b.
作者信息
Barbour M L
机构信息
John Radcliff Hospital, Oxford, England.
出版信息
Emerg Infect Dis. 1996 Jul-Sep;2(3):176-82. doi: 10.3201/eid0203.960303.
Abstract
Pharyngeal carriage of Haemophilus influenzae type b (Hib) is important in the transmission of Hib organisms, the pathogenesis of Hib disease, and the development of immunity to the bacterium. The remarkable success of current vaccination programs against Hib has been due in part to the effect of conjugate Hib vaccines in decreasing carriage of Hib. This review explores evidence for this effect, and discusses the possible mechanisms of the mucosal influence of Hib conjugate vaccines.
摘要
b型流感嗜血杆菌（Hib）的咽部携带在Hib病原体传播、Hib疾病发病机制以及对该细菌免疫的发展中具有重要意义。当前针对Hib的疫苗接种计划取得显著成功，部分原因在于结合型Hib疫苗在降低Hib携带方面的作用。本综述探讨了这一作用的证据，并讨论了Hib结合疫苗产生黏膜影响的可能机制。
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1
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J Exp Med. 1931 Mar 31;53(4):471-92. doi: 10.1084/jem.53.4.471.
2
An improved antiserum agar method for detecting carriage of Haemophilus influenzae type b.一种用于检测b型流感嗜血杆菌携带情况的改良抗血清琼脂方法。
Eur J Clin Microbiol Infect Dis. 1993 Mar;12(3):215-7. doi: 10.1007/BF01967116.
3
Antibody persistence after accelerated immunisation against Haemophilus influenzae type b.b型流感嗜血杆菌加速免疫后的抗体持久性
BMJ. 1993 Apr 10;306(6883):971-2. doi: 10.1136/bmj.306.6883.971.
4
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J Pediatr. 1993 Apr;122(4):517-23. doi: 10.1016/s0022-3476(05)83529-2.
5
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J Infect Dis. 1993 Feb;167(2):365-71. doi: 10.1093/infdis/167.2.365.
6
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JAMA. 1993 Jan 13;269(2):246-8.
7
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8
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