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结直肠癌的早期检测

The early detection of colorectal cancer.

作者信息

Miller S F, Knight A R

出版信息

Cancer. 1977 Aug;40(2):945-9. doi: 10.1002/1097-0142(197708)40:2<945::aid-cncr2820400253>3.0.co;2-f.

Abstract

A review of the American Cancer Society's statistics for colorectal cancer indicates that there has been little improvements in the survival rate for this disease in the past 25 years. Although there have been advances in surgical techniques, radiation therapy, and chemotherapy, the key to improved survival rates is earlier diagnosis. A significant percentage of patients continues to present with regional or distal metastasis at the time of their initial diagnosis. Both proctosigmoidoscopy and guaiac impregnated filter slide paper methods have been productive in diagnosing this disease at an earlier stage. The "Hemoccult" test, however, is inexpensive, can be used on a routine basis, is easier for patients to perform themselves, and is aesthetically pleasing. It represents a significant cost savings compared to proctosigmoidoscopy and should be advocated for routine use in all patients over 40 years of age. Although there continues to be a role for local and regional mass screening programs, significant improvements in colorectal survival rates cannot be expected until routine application of this type of screening is practiced.

摘要

美国癌症协会关于结直肠癌的统计数据回顾表明,在过去25年里,这种疾病的生存率几乎没有提高。尽管手术技术、放射治疗和化疗都取得了进展,但提高生存率的关键在于早期诊断。相当比例的患者在初次诊断时仍表现为局部或远处转移。直肠乙状结肠镜检查和愈创木脂浸渍滤纸片法在早期诊断这种疾病方面都很有效。然而,“潜血”试验价格低廉,可常规使用,患者自己操作更容易,而且外观上更美观。与直肠乙状结肠镜检查相比,它能显著节省成本,应提倡在所有40岁以上的患者中常规使用。尽管局部和区域大规模筛查项目仍有作用,但在这种筛查方法得到常规应用之前,结直肠癌生存率的显著提高是无法实现的。

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