Pollock A V
Department of Surgery, Scarborough Hospital, UK.
Eur J Surg Suppl. 1996(576):13-5.
While infection is a consequence of invasion of microorganisms, sepsis is a phenomenon of the host. Systemic inflammatory response syndrome (SIRS), "severe sepsis", and "septic shock" may occur without infection, or persist, and lead to multiple organ dysfunction syndrome (MODS) after infection has been eradicated with antibiotics and surgery. The mechanisms responsible for these phenomena are increasingly being elucidated, but we cannot yet define when infective sepsis merges into non-infective sepsis. What do we know is they are just as lethal as each other.
虽然感染是微生物入侵的结果，但脓毒症是宿主的一种现象。全身炎症反应综合征（SIRS）、“严重脓毒症”和“脓毒性休克”可能在没有感染的情况下发生，或持续存在，并在使用抗生素和手术根除感染后导致多器官功能障碍综合征（MODS）。导致这些现象的机制越来越清楚，但我们尚无法界定感染性脓毒症何时转变为非感染性脓毒症。我们所知道的是，它们的致死性是一样的。
