Reemst P H, van Goor H, Goris R J
Department of Surgery, University Hospital, Nijmegen, The Netherlands.
Eur J Surg Suppl. 1996(576):47-8; discussion 49.
Some patients with peritonitis develop a septic response without a detectable infective focus. It is suggested that an immunological dysfunction is responsible for this so called tertiary peritonitis. The role of the gastrointestinal tract in the development of multiple organ dysfunction syndrome (MODS) is discussed. In patients with tertiary peritonitis treatment should be directed towards restoration of the immunological balance, which is probably more important than the elimination of microorganisms with antibiotics.
一些腹膜炎患者会出现脓毒症反应，但未发现感染灶。有人认为免疫功能障碍是导致这种所谓的继发性腹膜炎的原因。本文讨论了胃肠道在多器官功能障碍综合征（MODS）发生发展中的作用。对于继发性腹膜炎患者，治疗应致力于恢复免疫平衡，这可能比用抗生素清除微生物更为重要。
