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泰国中部HIV-1感染率高的静脉吸毒者中未检测到HTLV-I/II感染证据。

No proof of HTLV-I/II in intravenous drug abusers with a high rate of HIV-1 infection in central Thailand.

作者信息

Saguanwongse S, Muangpom A, Ruchusatsawat N, Wongcheree S, Warachit P, Miyamura K, Yamazaki S, Honda M

机构信息

Virus Research Institute, Department of Medical Sciences, Thailand.

出版信息

Microbiol Immunol. 1996;40(9):639-44. doi: 10.1111/j.1348-0421.1996.tb01121.x.

DOI:10.1111/j.1348-0421.1996.tb01121.x
PMID:8908608
Abstract

Serum specimens of 1,074 intravenous drug abusers (IVDA) were examined for infection with HIV-1, HTLV-I and HTLV-II in central Thailand. Three hundred and sixty-two of the specimens were seropositive for HIV-1 (33.7%). The HIV-1 seropositive IVDAs exhibited increased seropositivity with age through group 40-44 and significantly decreased seropositivity over the age of 45. In contrast, no seropositivity to either HTLV-I or -II was detected in the samples tested by a particle-agglutination assay for HTLV followed by type-specific Western blotting for HTLV. Reference to previous reports suggested that the rate of HIV infection in IVDAs has decreased with no HTLV-I or HTLV-II in Thailand when compared with that of the HIV infection in 1992.

摘要

在泰国中部,对1074名静脉注射吸毒者(IVDA)的血清样本进行了HIV-1、HTLV-I和HTLV-II感染检测。其中362份样本HIV-1血清学检测呈阳性(33.7%)。HIV-1血清学检测呈阳性的IVDA在40至44岁组中随着年龄增长血清学阳性率增加,而45岁以上血清学阳性率显著下降。相比之下,通过HTLV颗粒凝集试验及随后的HTLV型特异性蛋白质印迹法检测的样本中,未检测到HTLV-I或-II的血清学阳性。参考之前的报告表明,与1992年的HIV感染情况相比,泰国IVDA中HIV感染率有所下降,且未发现HTLV-I或-II感染。

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