放射免疫分析法测定血清游离甲状腺素
Determination of free thyroxine in serum by radioimmunoassay.
作者信息
Jiang N S, Tue K A
出版信息
Clin Chem. 1977 Sep;23(9):1679-83.
We describe a sensitive and specific radioimmunoassay for free thyroxine, directly determined in the diffusate obtained from equilibrium dialysis of serum. The intra- and interassay precisions were 7.5 +/- 0.27 and 9.1 +/- 0.58 ng/liter (mean +/- SD), respectively. The free thyroxine concentrations of normal persons and patients with thyroid disease were as follows: normal, 7.6 +/- 1.7; euthyroid patients receiving phenytoin, 6.9 +/- 1.4; hypothyroidism, 2.9 +/- 1.3; and hyperthyroidism, 32.3 +/- 12.3 ng/liter (mean +/- SD).
我们描述了一种用于游离甲状腺素的灵敏且特异的放射免疫分析方法，该方法可直接对血清平衡透析所得透析液中的游离甲状腺素进行测定。批内和批间精密度分别为7.5±0.27和9.1±0.58 ng/升（均值±标准差）。正常人和甲状腺疾病患者的游离甲状腺素浓度如下：正常人，7.6±1.7；接受苯妥英治疗的甲状腺功能正常患者，6.9±1.4；甲状腺功能减退，2.9±1.3；甲状腺功能亢进，32.3±12.3 ng/升（均值±标准差）。
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