Blumenfeld T A, Hertelendy W G, Ford S H
Clin Chem. 1977 Sep;23(9):1705-10.
Specimens of skin-puncture serum and plasma and venous serum were simultaneously obtained from healthy adults and in each specimen the concentrations of 12 chemical constituents were measured. No clinically important difference was found in the concentrations of the constituents measured in skin-puncture serum and plasma with or without warming the skin before puncture. When the concentration of each of the measured constituents was compared in skin-puncture specimens and venous serum there were important differences in the concentrations of glucose, potassium, total protein, and calcium. Except for glucose, the concentrations of these were higher in venous serum. The degree of hemolysis was the same in skin-puncture serum and plasma, but less in venous serum. The greater hemolysis in skin-puncture specimens was not reflected in a clinically important increase in the values of lactate dehydrogenase and potassium. We conclude that there is a difference in the concentration of some chemical constituents in skin-puncture specimens and venous serum and that these differences should be considered when results for these types of specimens are compared.
从健康成年人身上同时采集皮肤穿刺血清、血浆和静脉血清样本，并测定每个样本中12种化学成分的浓度。在穿刺前对皮肤进行或不进行加温的情况下，皮肤穿刺血清和血浆中所测成分的浓度未发现具有临床意义的差异。当比较皮肤穿刺样本和静脉血清中各被测成分的浓度时，葡萄糖、钾、总蛋白和钙的浓度存在显著差异。除葡萄糖外，这些成分在静脉血清中的浓度更高。皮肤穿刺血清和血浆中的溶血程度相同，但静脉血清中的溶血程度较小。皮肤穿刺样本中较大程度的溶血并未在乳酸脱氢酶和钾值的临床上显著增加中体现出来。我们得出结论，皮肤穿刺样本和静脉血清中某些化学成分的浓度存在差异，在比较这些类型样本的结果时应考虑这些差异。
