Shen S X, Wang H B, Chen Z W, Shen Y E, Fu H, Wu C E, Ye T T, Wang J J, Wang K A, Li T L, Yang Z, LaPorte R E, Dorman J S
Children's Hospital, Shanghai Medical University, China.
J Pediatr Endocrinol Metab. 1996 Jul-Aug;9(4):469-73. doi: 10.1515/jpem.1996.9.4.469.
A retrospective study on the incidence of insulin-dependent diabetes mellitus (IDDM) among children aged 0-14 years was carried out from 1989-1993 in urban Shanghai, China. The average annual population at risk (0-14 yr) consisted of 1,401,664 children. All the cases were collected from the hospitals (primary source) and from primary and middle schools and kindergartens (second source) with independent validation of case ascertainment. There were 53 IDDM cases from the primary source, 23 from the secondary source, with a total of 58. The ascertainment corrected total number of IDDM cases was 67 by the capture-recapture method. The average crude annual incidence rate was 0.83 [95% confidence interval (CI) 0.61-1.04] and ascertainment corrected incidence rate 0.96 (95% CI 0.80-1.12) per 100,000. Peak incidence fell in 1992 and in the 9 year-old group. The incidence of childhood IDDM in the urban districts of Shanghai was reconfirmed to be the lowest in the world but by comparing the results of former investigations a trend was found of increasing incidence of IDDM.
1989年至1993年期间,在中国上海市区对0至14岁儿童中胰岛素依赖型糖尿病(IDDM)的发病率进行了一项回顾性研究。平均每年的危险人群(0至14岁)包括1,401,664名儿童。所有病例均从医院(主要来源)以及中小学和幼儿园(次要来源)收集,并对病例确诊进行独立验证。主要来源有53例IDDM病例,次要来源有23例,共计58例。通过捕获-再捕获法确定的IDDM病例校正总数为67例。平均粗年发病率为每10万人0.83[95%置信区间(CI)0.61 - 1.04],确诊校正发病率为0.96(95%CI 0.80 - 1.12)。发病率高峰出现在1992年和9岁年龄组。再次证实上海市区儿童IDDM的发病率是世界上最低的,但通过比较以前的调查结果发现IDDM发病率有上升趋势。