Ramachandran A, Snehalatha C, Krishnaswamy C V
Diabetes Research Centre, Royapuram, Madras, India.
Diabetes Res Clin Pract. 1996 Oct;34(2):79-82. doi: 10.1016/s0168-8227(96)01338-1.
This study was carried out to estimate the incidence of childhood insulin dependent diabetes mellitus (IDDM) in an urban southern Indian, population. A registry for IDDM has been set up in the city of Madras. South India. Details of newly diagnosed IDDM children, aged less than 15 years, were analysed retrospectively, for a period of 1991-1994. Primary sources were government and service hospitals, large diabetes clinics and secondary sources were diabetes camp, private diabetologists and endocrinologists. A capture-recapture method was used and the estimate of case in the population (1991 census) was calculated. Incidence (case/100,000) was calculated in the total group and then for boys and girls separately. The incidence for the 4 year period was 10.5/100,000/year (CI 5.0). The corresponding values for boys and girls were 12.6 +/- 11 and 9.6 +/- 4.7 respectively. The peak incidence was between 10 and 12 years. This is the first population based incidence data from India and showed that the incidence of childhood IDDM is not low in urban children.
本研究旨在估算印度南部城市人群中儿童胰岛素依赖型糖尿病（IDDM）的发病率。在印度南部的马德拉斯市已建立了一个IDDM登记处。对1991年至1994年期间新诊断出的年龄小于15岁的IDDM儿童的详细情况进行了回顾性分析。主要来源是政府和服务医院、大型糖尿病诊所，次要来源是糖尿病营地、私人糖尿病专家和内分泌专家。采用了捕获-再捕获方法，并计算了该人群（1991年人口普查）中的病例估计数。计算了总人群以及男孩和女孩各自的发病率（病例数/10万）。4年期间的发病率为每年10.5/10万（可信区间5.0）。男孩和女孩的相应值分别为12.6±11和9.6±4.7。发病高峰在10至12岁之间。这是来自印度的首个基于人群的发病率数据，表明城市儿童中儿童IDDM的发病率并不低。
