Tranvan A, Pezen D S, Medenica M, Michelson G C, Vogelzang N, Soltani K M
Section of Dermatology, University of Chicago Medical Center, USA.
J Am Acad Dermatol. 1996 Nov;35(5 Pt 2):865-7. doi: 10.1016/s0190-9622(96)90106-1.
Linear IgA bullous dermatosis (LABD) in adults is characterized by subepidermal bullae associated with a linear deposition of IgA at the basement membrane zone. Its cause is unclear, although it appears to have an immune-mediated basis. The development of LABD in a cancer patient undergoing immunotherapy has been described in the French literature. We describe a similar case of LABD arising in a patient while undergoing interleukin-2 immunotherapy for renal cell carcinoma.
成人线状IgA大疱性皮肤病（LABD）的特征是表皮下大疱，伴有IgA在基底膜带呈线状沉积。其病因尚不清楚，尽管似乎有免疫介导的基础。法国文献中曾描述过一名接受免疫治疗的癌症患者发生LABD的情况。我们描述了一名在接受白细胞介素-2免疫治疗肾细胞癌期间发生LABD的类似病例。
