Augustinsson L E, Eliasson T, Mannheimer C
Department of Neurosurgery, Sahlgrenska University Hospital, Göteborg, Sweden.
Stereotact Funct Neurosurg. 1995;65(1-4):136-41. doi: 10.1159/000098685.
Since 1985, 225 patients suffering from severe pectoris due to New York Heart Association classes III-IV have been treated with spinal cord stimulation (SCS). All patients have been considered not suitable for open heart surgery by technical reasons. The long-term follow-up has shown a very good positive response to stimulation with pain relief, less intake of medication and increased quality of life. Several invasive studies with catheters in the coronary sinus and peripheral arteries have shown a significant improvement with stimulation regarding heart muscle lactate metabolism, blood flow in the coronary sinus and oxygen demand. Recordings with the so-called Holter technique have demonstrated that SCS does not create arrhythmias, and pacing studies that SCS does not mask ischemia at extreme workload. In conclusion, apart from the positive effect on the quality of life, SCS in angina pectoris has demonstrated antianginal and anti-ischemic effects. The clinical results and the physiological and hemodynamic measurements will be presented in detail.
自1985年以来,225例纽约心脏协会III-IV级重度心绞痛患者接受了脊髓刺激(SCS)治疗。由于技术原因,所有患者均被认为不适合进行心脏直视手术。长期随访显示,刺激治疗产生了非常好的积极反应,疼痛减轻,药物摄入量减少,生活质量提高。几项在冠状窦和外周动脉中使用导管的侵入性研究表明,刺激可使心肌乳酸代谢、冠状窦血流和氧需求有显著改善。使用所谓的动态心电图技术进行的记录表明,SCS不会引发心律失常,起搏研究表明,SCS在极端负荷下不会掩盖缺血情况。总之,除了对生活质量有积极影响外,SCS在心绞痛方面还显示出抗心绞痛和抗缺血作用。将详细介绍临床结果以及生理和血流动力学测量结果。