Cunningham J, Temple W J, Mitchell P, Nixon J A, Preshaw R M, Hagen N A
Department of Surgery, Dalhousie University, Halifax, Nova Scotia, Canada.
Ann Surg. 1996 Nov;224(5):598-602. doi: 10.1097/00000658-199611000-00003.
The Cooperative Hernia Study assessed postoperative pain in a prospective trial as part of a larger study looking at the recurrence rate and other morbidity of the Bassini, McVay, and Shouldice repairs.
Patients were randomized to one of three surgical hernia repairs. Patients were seen in follow-up at 6, 12, and 24 months and were assessed for the presence of pain, numbness, paresthesia, and recurrence.
Three hundred fifteen patients were seen in follow-up, with 276 seen at the 2-year mark. At 1 year, 62.9% of patients had groin or inguinal pain and 11.9% of patients had moderate to severe pain; 53.6% had pain and 10.6% of patients continued to report moderate to severe pain 2 years postoperatively. The predictors for long-term postoperative pain were as follows: absence of a visible bulge before the operation (p < 0.001); presence of numbness in the surgical area postoperatively (p < 0.05); and patient requirement of more than 4 weeks out of work postoperatively (p < 0.004). Three distinct chronic pains were identified. The most common and most severe pain was somatic, localized to the common ligamentous insertion to the public tubercle. The second was neuropathic and was referable to the ilioinguinal or genitofemoral nerve distribution. This was likely because of injury to the genitofemoral nerves, either at surgery or subsequently by encroachment of scar. The third pain was visceral, ejaculatory pain. Twenty-four percent of patients had postoperative numbness at 2 years, independent of the type of repair. Numbness was most common in the distribution of cutaneous branches of the ilioinguinal and iliohypogastric nerves.
Pain or numbness are common late sequelae of traditional external surgical hernia repairs. Strategies need to be developed to reduce the risk of these complications.
疝协作研究在一项前瞻性试验中评估了术后疼痛,该试验是一项更大规模研究的一部分,该研究关注巴西尼修补术、麦克维修补术和肖尔代斯修补术的复发率及其他发病率。
患者被随机分配至三种手术疝修补术之一。在术后6个月、12个月和24个月对患者进行随访,评估疼痛、麻木、感觉异常和复发情况。
共有315例患者接受随访,其中276例患者随访至2年。1年时,62.9%的患者有腹股沟或腹股沟区疼痛,11.9%的患者有中度至重度疼痛;术后2年,53.6%的患者有疼痛,10.6%的患者仍报告有中度至重度疼痛。术后长期疼痛的预测因素如下:术前无可见肿块(p<0.001);术后手术区域存在麻木(p<0.05);患者术后需要超过4周的休假时间(p<0.004)。确定了三种不同的慢性疼痛。最常见、最严重的疼痛是躯体性疼痛,局限于耻骨结节的常见韧带附着处。第二种是神经性疼痛,可归因于髂腹股沟或生殖股神经分布区。这可能是由于生殖股神经在手术时或随后因瘢痕侵犯而受损。第三种疼痛是内脏性射精疼痛。24%的患者在2年时有术后麻木,与修补类型无关。麻木在髂腹股沟和髂腹下神经皮支分布区最为常见。
疼痛或麻木是传统外科外疝修补术常见的晚期后遗症。需要制定策略来降低这些并发症的风险。