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五例铝中毒的随访研究。

A follow-up study of five cases of aluminosis.

作者信息

Sjögren B, Ljunggren K G, Almkvist O, Frech W, Basun H

机构信息

Department of Occupational Medicine, Swedish National Institute for Working Life, Solna.

出版信息

Int Arch Occup Environ Health. 1996;68(3):161-4. doi: 10.1007/BF00381625.

DOI:10.1007/BF00381625
PMID:8919843
Abstract

Five men were investigated after having pulmonary aluminosis due to exposure to aluminium pyrotechnic flake powder during the late 1940s. Two of the men had died 6 years and 20 years after exposure respectively, due to their lung disease. One man had died from heart failure 34 years after the end of exposure. Today, more than 40 years after exposure, two men were available for investigation. They had no respiratory symptoms and their vital lung capacities had not deteriorated during these years. One of the two survivors had developed a dementia with motor disturbances, which is not consistent with Alzheimer's dementia. This man had a very high concentration of aluminium in his cerebrospinal fluid. The other survivor had a normal concentration and was not demented.

摘要

20世纪40年代末,五名男子因接触铝粉烟火剂粉末而患上肺铝尘肺,随后接受了调查。其中两名男子分别在接触后的6年和20年因肺部疾病死亡。一名男子在接触结束34年后死于心力衰竭。如今,在接触40多年后,有两名男子可供调查。他们没有呼吸道症状,这些年来他们的肺活量也没有恶化。两名幸存者中的一名患上了伴有运动障碍的痴呆症,这与阿尔茨海默病性痴呆不符。这名男子的脑脊液中铝含量非常高。另一名幸存者的铝含量正常,没有患痴呆症。

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本文引用的文献

1
Spirometric studies in normal subjects. I. Forced expirograms in subjects between 7 and 70 years of age.正常受试者的肺量计研究。I. 7至70岁受试者的用力呼气图。
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Pulmonary fibrosis and encephalopathy associated with the inhalation of aluminium dust.与吸入铝尘相关的肺纤维化和脑病。
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Episodic memory functioning in a community-based sample of old adults with major depression: utilization of cognitive support.在患有重度抑郁症的老年社区样本中情景记忆功能:认知支持的利用情况
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Aluminosis and dementia.铝中毒与痴呆症。
Lancet. 1994 Oct 22;344(8930):1154. doi: 10.1016/s0140-6736(94)90659-9.
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Internal load of aluminum and the central nervous system function of aluminum welders.铝焊工的铝体内负荷与中枢神经系统功能
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Dialysis encephalopathy and aluminum exposure: an epidemiologic analysis.透析性脑病与铝暴露:一项流行病学分析。
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Aluminium in the blood and urine of industrially exposed workers.从事工业生产的工人血液和尿液中的铝含量。
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