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一种改良的白细胞迁移试验作为恶性和非恶性胃黏膜改变的指标。

A modified leucocyte migration assay as indicator of malignant and non-malignant gastric mucosal alteration.

作者信息

Zöller M, Matzku S, Rapp W, Schulz U

出版信息

Digestion. 1977;15(5):373-84. doi: 10.1159/000198025.

DOI:10.1159/000198025
PMID:892259
Abstract

When gastric cancer patients' leucocytes were exposed to a panel of tumour extracts, leucocyte migration reactivity was "positive" before operation (90% of cases), it declined after surgery and it reappeared in patients with local recurrence or metastases. In patients with non-malignant gastric diseases, "positive" reactivity against tumour extracts was associated almost exclusively with atrophic gastritis with and without intestinal metaplasia (24/43 cases). "Positive" patients also showed a pathological migration index with an extract of normal gastric mucosa.

摘要

当胃癌患者的白细胞暴露于一组肿瘤提取物时,术前白细胞迁移反应性为“阳性”(90%的病例),术后下降,在局部复发或转移的患者中再次出现。在非恶性胃部疾病患者中,对肿瘤提取物的“阳性”反应几乎仅与伴有或不伴有肠化生的萎缩性胃炎相关(43例中的24例)。“阳性”患者对正常胃黏膜提取物也显示出病理性迁移指数。

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A modified leucocyte migration assay as indicator of malignant and non-malignant gastric mucosal alteration.一种改良的白细胞迁移试验作为恶性和非恶性胃黏膜改变的指标。
Digestion. 1977;15(5):373-84. doi: 10.1159/000198025.
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Aust N Z J Surg. 1981 Oct;51(5):434-9. doi: 10.1111/j.1445-2197.1981.tb05978.x.
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Leukocyte migration studies in gastric cancer detection: an approach toward improved specificity and sensitivity.白细胞迁移研究在胃癌检测中的应用:提高特异性和敏感性的方法。
J Natl Cancer Inst. 1977 Apr;58(4):897-904. doi: 10.1093/jnci/58.4.897.
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