Osher Y, Cloninger C R, Belmaker R H
Ministry of Health Mental Health Center, Ben Gurion University of the Negev, Beersheva, Israel.
J Psychiatr Res. 1996 Sep-Oct;30(5):353-7. doi: 10.1016/0022-3956(96)00023-4.
Researchers using various psychological measures and instruments have concluded that the personality of remitted bipolars and normal controls are essentially similar. We recently suggested that specific personality traits might be genetic markers for manic-depressive illness. The Tridimensional Personality Questionnaire (TPQ) is a personality questionnaire with heritable subscales and hypothesized anchoring in neurochemistry. We studied the personality of euthymic bipolar manic depressive patients using the TPQ. Subjects were volunteers from the out-patient Lithium Clinic. TPQs were individually administered to 50 euthymic bipolar patients. Persistence is significantly reduced, and harm avoidance and reward dependence significantly increased, compared with U.S. norms. These traits may be part of the genetic diathesis for manic-depressive illness.
使用各种心理测量方法和工具的研究人员得出结论，缓解期双相情感障碍患者和正常对照组的人格本质上是相似的。我们最近提出，特定的人格特质可能是躁郁症的遗传标记。三维人格问卷（TPQ）是一种人格问卷，具有可遗传的分量表，并假设其在神经化学方面有依据。我们使用TPQ研究了心境正常的双相躁郁症患者的人格。研究对象是门诊锂盐诊所的志愿者。对50名心境正常的双相情感障碍患者分别进行了TPQ测试。与美国的常模相比，坚持性显著降低，而回避伤害和奖赏依赖显著增加。这些特质可能是躁郁症遗传素质的一部分。
