Deswal A, Follansbee W P
University of Pittsburgh School of Medicine, Pennsylvania, USA.
Rheum Dis Clin North Am. 1996 Nov;22(4):841-60. doi: 10.1016/s0889-857x(05)70304-5.
In summary, cardiac involvement in systemic sclerosis can be manifested as myocardial disease, pericardial disease, conduction system disease, or arrhythmias. Clinical cardiac involvement is a poor prognostic factor. Asymptomatic cardiac abnormalities are frequent, and all cardiac abnormalities are seen more often in diffuse scleroderma. Unlike other organs, the role of vascular involvement is unclear. At present, treatment of cardiac scleroderma is essentially symptomatic and empiric. The role of vasodilation and immunosuppression needs further exploration.
总之，系统性硬化症的心脏受累可表现为心肌病、心包疾病、传导系统疾病或心律失常。临床心脏受累是一个不良预后因素。无症状性心脏异常很常见，且所有心脏异常在弥漫性硬皮病中更常见。与其他器官不同，血管受累的作用尚不清楚。目前，心脏硬皮病的治疗基本上是对症和经验性的。血管扩张和免疫抑制的作用需要进一步探索。
