Kisliakov Iu Ia
Biofizika. 1996 May-Jun;41(3):681-5.
A model of diffusive O2 transport in erythrocyte and surrounding plasma is suggested which allows for the calculation of pO2 distribution in a 3-dimensional capillary region. The dynamic of O2 diffusion inside and outside erythrocyte and reaction kinetics of red blood cell are considered. The finite differential method is used to obtain a pO2 profiles as a solution of the differential equations. Resulting pO2 profiles exhibit large peri-oxyhemoglobin and small plasma pO2 gradients. Such O2 transport peculiarity in capillary creates optimal conditions for tissue O2 supply.
提出了一种红细胞及其周围血浆中氧气扩散传输模型，该模型可用于计算三维毛细血管区域内的氧分压分布。考虑了红细胞内外氧气扩散的动力学以及红细胞的反应动力学。采用有限差分法求解微分方程以获得氧分压分布曲线。所得氧分压分布曲线显示，血红蛋白周围的氧分压梯度较大，而血浆中的氧分压梯度较小。毛细血管中这种氧气传输特性为组织供氧创造了最佳条件。
