Reiter P
CDC, National Center for Infectious Diseases, San Juan Laboratories, Puerto Rico 00921-3200.
Bull Soc Pathol Exot. 1996;89(2):95-6; discussion 97.
Dengue fever is endemic from Argentina to Mexico, where serotypes 1, 2 and 4 are in wide circulation. After an absence of almost 20 years, serotype 3 arrived in Central America in late 1994. Over the past decade dengue has become a major public health problem in many of these countries, with an increase in the prevalence of dengue haemorrhagic fever and in the number of fatal cases. The situation is not new; there is evidence of a least eight pandemics from the early 19th century until the initiation of the Aedes aegypti eradication campaign in 1947. The resurgence of serious disease was predicted in the early 1980's, and has followed a pattern of increasing severity observed 20 years earlier in Asia.
登革热在从阿根廷到墨西哥的地区呈地方性流行,其中1型、2型和4型血清型广泛传播。在几乎消失了20年后,3型血清型于1994年末抵达中美洲。在过去十年中,登革热已成为这些国家中许多国家的主要公共卫生问题,登革出血热的患病率和死亡病例数都有所增加。这种情况并非新鲜事;有证据表明,从19世纪初到1947年开展埃及伊蚊根除运动开始,至少发生过八次大流行。20世纪80年代初曾预测严重疾病会再度出现,并且其严重程度呈上升趋势,这与20年前在亚洲观察到的情况一致。