Derouin F
Laboratoire de Parasitologie-Mycologie Hôpital Saint-Louis, Paris.
Bull Acad Natl Med. 1996 Apr;180(4):859-68; discussion 868-70.
Nosocomial invasive aspergillosis has emerged as a major infectious complication in patients with profound immunodeficiency. Thus, preventive measures must be instautred in hospital wards "at risk for aspergillosis" (mainly haematology, bone marrow transplant and organ transplant units) in order to prevent the outer risk of contamination. These comprise a sequential follow-up of air and surface contamination and molecular analysis of isolated fungal strains for further analysis of the epidemiology of Aspergillus in the hospital environment. We also recommend that biological, clinical and environmental data should be centralized and analyzed monthly by a specialized staff composed of physicians, mycologists, heath care and administrative personnel in order to define the optimum strategy for prevention within the hospital.
医院获得性侵袭性曲霉病已成为严重免疫缺陷患者的主要感染并发症。因此，必须在“有曲霉病风险”的医院病房（主要是血液科、骨髓移植和器官移植科室）采取预防措施，以防止外部污染风险。这些措施包括对空气和表面污染进行连续监测，以及对分离出的真菌菌株进行分子分析，以便进一步分析医院环境中曲霉的流行病学情况。我们还建议，应由医生、真菌学家、医护人员和行政人员组成的专业团队每月集中收集并分析生物学、临床和环境数据，以便确定医院内最佳的预防策略。
