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大鼠鼻中隔软骨细胞增殖和基质形成的区域差异。[³H] - 胸腺嘧啶核苷和[³⁵S] - 硫酸盐掺入研究。

Regional variations in cell proliferation and matrix formation in the cartilaginous nasal septum of the rat. [3H]-Thymidine and [35S]-sulfate incorporation studies.

作者信息

Kvinnsland S

出版信息

Growth. 1977 Jun;41(2):85-93.

PMID:892582
Abstract

The anterior, middle and posterior regions of the cartilaginous nasal septum were studied using [3H]-thymidine and [35S]-sulfate incorporation. Varying intensity in both cell proliferation and matrix formation were found at different developmental stages. Taking the whole experimental period under consideration (from 0-21 days) the greatest proliferative activities were found in the anterior and posterior regions respectively, whereas the greatest activities in matrix formation were found in the middle and posterior regions (cpm [3H]-thymidine/DNA and cpm [35S]-sulfate/DNA). An increase in proliferation was followed shortly after by an increase in matrix formation.

摘要

利用[3H]-胸腺嘧啶核苷掺入法和[35S]-硫酸盐掺入法对鼻中隔软骨的前、中、后区域进行了研究。在不同发育阶段发现细胞增殖和基质形成的强度各不相同。考虑整个实验期(0至21天),在前部和后部区域分别发现了最高的增殖活性,而在中部和后部区域发现了最高的基质形成活性([3H]-胸腺嘧啶核苷/DNA的每分钟计数和[35S]-硫酸盐/DNA的每分钟计数)。增殖增加后不久,基质形成也随之增加。

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