Rosselli M, Ardila A
Fundacion Universitaria, Konrad Lorenz, Bogotá, Colombia.
J Clin Exp Neuropsychol. 1996 Feb;18(1):122-35. doi: 10.1080/01688639608408268.
One hundred and eighty-three participants were divided into three groups containing: 61 cocaine-dependent; 59 polydrug-dependent; and 63 normal subjects. All were evaluated using a basic neuropsychological assessment battery. The dependent groups exhibited significantly lower scores on short-term memory, attention, and concept formation tests. Performance on some subtests correlated negatively with the length of dependency and frequency of substance use. As compared with the control group, the dependent groups exhibited significant differences in the following personal and family areas: (a) depression and anxiety traits; (b) self-aggression and lack of fear in childhood; (c) family history of substance dependency; and (d) difficulties with interpersonal relationships. The operation of predisposing developmental factors for substance dependence is suggested.
183名参与者被分为三组：61名可卡因依赖者；59名多种药物依赖者；63名正常受试者。所有人都使用基本的神经心理学评估量表进行了评估。依赖组在短期记忆、注意力和概念形成测试中的得分显著较低。一些子测试的表现与依赖时间长度和物质使用频率呈负相关。与对照组相比，依赖组在以下个人和家庭方面存在显著差异：(a)抑郁和焦虑特质；(b)童年期的自我攻击和无畏；(c)物质依赖家族史；(d)人际关系困难。研究表明存在导致物质依赖的发育易感因素。
