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[通过激光多普勒血流仪评估异氟烷对耳蜗血流的影响]

[The evaluation of isoflurane's effect on the cochlear blood flow by laser doppler flowmetry].

作者信息

Albera R, Tondolo E, Ferrero V, Pignocchino P, Pallavicino F

机构信息

II Clinica ORL, Università di Torino.

出版信息

Acta Otorhinolaryngol Ital. 1995 Aug;15(4):289-93.

PMID:8928660
Abstract

Laser-Doppler flowetry is actually the method of choice in cochlear blood flow measurement. The Authors analyze, by means of laser doppler flowmetry, the effect of isoflurane, an anesthetic drug with an hypotensive effect, on cochlear blood flow on 10 patients submitted to miringoplasty. A slight increase of cochlear blood flow was recorded in each subject nevertheless a significative reduction of systemic pressure. Since normally hypotension determines a reduction of cochlear blood flow, the Authors state that isoflurane has a protective effect on this microcircular district.

摘要

激光多普勒血流仪实际上是耳蜗血流测量的首选方法。作者通过激光多普勒血流仪分析了异氟烷(一种具有降压作用的麻醉药物)对10例接受鼓膜成形术患者耳蜗血流的影响。尽管全身血压显著降低,但在每个受试者中均记录到耳蜗血流略有增加。由于正常情况下低血压会导致耳蜗血流减少,作者指出异氟烷对该微循环区域具有保护作用。

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