Bardales R H, Suhrland M J, Korourian S, Schaefer R F, Hanna E Y, Stanley M W
Department of Pathology, University of Arkansas for Medical Sciences, John L. McClellan Memorial Veterans Hospital, Little Rock, Arkansas 72205, USA.
Am J Clin Pathol. 1996 Nov;106(5):615-9. doi: 10.1093/ajcp/106.5.615.
Approximately 150 cases of thyroglossal duct carcinoma, predominantly of the papillary type, have been reported, but the preoperative fine-needle aspiration (FNA) diagnosis of such neoplasms has rarely been cited. The authors describe FNA findings in four samples obtained from three patients who were 29, 50, and 83 years of age, histologically diagnosed as papillary (n = 2) and squamous (n = 1) thyroglossal duct carcinomas. Atypia and squamous cell carcinoma were the FNA diagnoses in the patients with papillary carcinomas. The remaining case was correctly diagnosed as keratinizing squamous cell carcinoma. Cellularity was scant in two cases and moderate in one, and all displayed a cystic background. The authors also reviewed FNA features in 11 papillary and 2 Hurthle cell carcinomas from the English language literature; diagnostic findings were present in less than one third of the cases. In conclusion, familiarity with the FNA findings of thyroglossal duct carcinoma is limited by its rarity. The presence of large, atypical squamous cells, or psammoma bodies, in the FNA material of a midline anterior cystic neck mass should suggest papillary thyroglossal duct carcinoma.
据报道，约有150例甲状舌管癌，主要为乳头状类型，但术前细针穿刺抽吸（FNA）诊断此类肿瘤的报道很少。作者描述了从三名年龄分别为29岁、50岁和83岁的患者获得的四个样本的FNA结果，这些患者经组织学诊断为乳头状（n = 2）和鳞状（n = 1）甲状舌管癌。非典型性和鳞状细胞癌是乳头状癌患者的FNA诊断结果。其余病例被正确诊断为角化性鳞状细胞癌。两例细胞数量稀少，一例中等，所有病例均显示囊性背景。作者还回顾了英文文献中11例乳头状癌和2例许特莱细胞癌的FNA特征；不到三分之一的病例有诊断性发现。总之，由于甲状舌管癌罕见，对其FNA结果的了解有限。中线前囊性颈部肿块的FNA材料中出现大的非典型鳞状细胞或砂粒体应提示乳头状甲状舌管癌。
