Rosenman K D, Stanbury M J, Reilly M J
Michigan State University, Department of Medicine, East Lansing, USA.
Scand J Work Environ Health. 1995;21 Suppl 2:73-6.
Michigan and New Jersey in the United States maintain silicosis disease registers. In 1988-1992, 372 cases of silicosis were confirmed in Michigan, and, in 1979-1992, 288 were confirmed in New Jersey. A proportionate mortality ratio (PMR) analysis was performed on data from 292 deceased silicotics. Increases in PMR values were found for nonmalignant respiratory disease (NMRD) and lung cancer. The PMR values for NMRD were statistically elevated in all the analyses. The overall proportionate cancer mortality ratio (PCMR) for lung cancer was 1.78 [95% confidence interval (95% CI) 1.22-2.61]. For patients having ever smoked cigarettes, the PCMR for lung cancer was 1.82 (95% CI 1.8-2.81). Never smoking silicotics had a lung cancer PCMR of 1.48 (95% CI 0.43-2.86). For those who had never applied for workers' compensation the corresponding PCMR was higher, 2.10 (95% CI 1.21-3.69), than for those who had applied, 1.45 (95% CI 0.70-2.99).
美国的密歇根州和新泽西州设有矽肺病登记册。1988 - 1992年期间,密歇根州确诊了372例矽肺病病例;1979 - 1992年期间,新泽西州确诊了288例。对292名已故矽肺病患者的数据进行了比例死亡率(PMR)分析。发现非恶性呼吸道疾病(NMRD)和肺癌的PMR值有所上升。在所有分析中,NMRD的PMR值在统计学上均有升高。肺癌的总体比例癌症死亡率(PCMR)为1.78 [95%置信区间(95%CI)1.22 - 2.61]。对于曾经吸烟的患者,肺癌的PCMR为1.82(95%CI 1.8 - 2.81)。从不吸烟的矽肺病患者肺癌PCMR为1.48(95%CI 0.43 - 2.86)。对于那些从未申请过工伤赔偿的人,相应的PCMR更高,为2.10(95%CI 1.21 - 3.69),高于申请过的人,后者为1.45(95%CI 0.70 - 2.99)。