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胃底折叠术后吞咽困难的评估与处理

Evaluation and management of postfundoplication dysphagia.

作者信息

Wo J M, Trus T L, Richardson W S, Hunter J G, Branum G D, Mauren S J, Waring J P

机构信息

Department of Medicine, Emory University School of Medicine, Atlanta, Georgia, USA.

出版信息

Am J Gastroenterol. 1996 Nov;91(11):2318-22.

PMID:8931410
Abstract

OBJECTIVES

Persistent dysphagia occurs in 3-24% of patients after fundoplication. There are virtually no data on the success or safety of endoscopic dilation to relieve postfundoplication dysphagia. The aim of this study was to review our experience with endoscopic management of patients with dysphagia after fundoplication.

MATERIALS AND METHODS

Thirty-five patients (mean age 49 yr; 12 males, 23 females) with dysphagia after fundoplication were referred for endoscopic dilation. Twenty-nine patients had undergone one fundoplication (group A), and six patients had undergone two or more operations (group B). The integrity of the fundoplication was evaluated by barium esophagram and upper endoscopy. Median follow-up after the initial postoperative dilation was 13 months.

RESULTS

The 29 patients in group A were dilated to a mean (+/- SD) of 52 +/- 4F during a mean (+/- SD) 1.9 +/- 1.1 dilation sessions per patient. No complications, such as disruption of the fundoplication, resulted from endoscopic dilation, and no one developed new reflux symptoms. Dysphagia resolved in 15 (52%) patients after dilation. The most important prognostic feature was endoscopic or radiological evidence of a slipped fundoplication. Dilation was successful in relieving dysphagia in only three of 11 (27%) patients with a slipped fundoplication, compared with 12 of 18 (67%) patients with an intact fundoplication (p = 0.05). Dysphagia resolved in only one of the six patients in group B.

CONCLUSIONS

Endoscopic dilation is safe and often effective in patients with postfundoplication dysphagia. However, patients with a slipped fundoplication or who have undergone multiple fundoplications respond poorly to endoscopic dilation.

摘要

目的

胃底折叠术后3% - 24%的患者会出现持续性吞咽困难。关于内镜扩张缓解胃底折叠术后吞咽困难的成功率或安全性,几乎没有相关数据。本研究的目的是回顾我们在内镜治疗胃底折叠术后吞咽困难患者方面的经验。

材料与方法

35例胃底折叠术后出现吞咽困难的患者(平均年龄49岁;男性12例,女性23例)被转诊接受内镜扩张治疗。29例患者接受过一次胃底折叠术(A组),6例患者接受过两次或更多次手术(B组)。通过食管钡餐造影和上消化道内镜检查评估胃底折叠术的完整性。首次术后扩张后的中位随访时间为13个月。

结果

A组的29例患者平均(±标准差)在每位患者1.9±1.1次扩张过程中被扩张至52±4F。内镜扩张未导致诸如胃底折叠术破裂等并发症,也没有患者出现新的反流症状。15例(52%)患者扩张后吞咽困难得到缓解。最重要的预后特征是内镜或放射学检查显示胃底折叠术滑脱。11例胃底折叠术滑脱的患者中只有3例(27%)扩张成功缓解了吞咽困难,而18例胃底折叠术完整的患者中有12例(67%)成功缓解(p = 0.05)。B组6例患者中只有1例吞咽困难得到缓解。

结论

内镜扩张治疗胃底折叠术后吞咽困难患者是安全的,且通常有效。然而,胃底折叠术滑脱或接受过多次胃底折叠术的患者对内镜扩张反应较差。

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