Robbins E G, Franceschi D, Barkin J S
University of Miami, School of Medicine/Mt. Sinai Medical Center, Division of Gastroenterology, Florida, USA.
Am J Gastroenterol. 1996 Nov;91(11):2414-7.
Secondary pancreatic tumors should be considered in those patients who present with a solitary pancreatic mass and who have had a previous nonpancreatic malignancy. The most common primary tumor origin of solitary pancreatic metastases is renal cell carcinoma, but many other primary sites have been reported. Radiological studies are useful for determining size and resectability, but a biopsy for tissue confirmation is required to differentiate primary and secondary pancreatic tumors. Survival data from patients who had solitary metastasis to other organ sites suggest that an aggressive surgical approach may improve survival. Characteristics of the primary tumor including tumor grade and histology may also affect prognosis. Prospective studies evaluating survival after surgical therapy have not been undertaken.
对于那些出现孤立性胰腺肿块且既往有非胰腺恶性肿瘤病史的患者,应考虑继发性胰腺肿瘤。孤立性胰腺转移瘤最常见的原发肿瘤起源是肾细胞癌,但也有许多其他原发部位的报道。影像学研究有助于确定肿瘤大小和可切除性,但需要进行活检以获取组织学确诊,以区分原发性和继发性胰腺肿瘤。有其他器官部位孤立性转移的患者的生存数据表明,积极的手术方法可能会提高生存率。原发性肿瘤的特征,包括肿瘤分级和组织学类型,也可能影响预后。尚未开展评估手术治疗后生存率的前瞻性研究。