无症状胃癌的临床病理研究
A clinicopathological study of asymptomatic gastric cancer.
作者信息
Matsukuma A, Furusawa M, Tomoda H, Seo Y
机构信息
Department of Gastroenterological Surgery, National Kyushu Cancer Center, Fukuoka, Japan.
出版信息
Br J Cancer. 1996 Nov;74(10):1647-50. doi: 10.1038/bjc.1996.603.
Abstract
The clinicopathological profiles of 419 patients with asymptomatic gastric cancer (AGC) first detected by gastric screening, were reviewed and compared with those of the 1727 patients with symptomatic gastric cancer (SGC). The incidence of AGC increased gradually and has amounted to 30% of the total resected cases in recent years. About 75% of AGC cases were of early cancer and 84% were negative for lymph node metastases. In contrast, only 33% of SGC cases were of early cancer and 57% were node positive. Curative resection was done in 97% of AGC and 75% of SGC. The cumulative 5 and 10 year survival rates of patients with curatively resected AGC were 85.2% and 72.2%, respectively, while those for patients with SGC were 66.8% and 55.4%. These data demonstrated that most patients with asymptomatic gastric cancers could expect a curative resection, i.e. have a better clinical outcome, than those with symptomatic cancer.
摘要
对419例经胃癌筛查首次发现的无症状胃癌（AGC）患者的临床病理特征进行了回顾，并与1727例有症状胃癌（SGC）患者的特征进行了比较。AGC的发病率逐渐上升，近年来已占全部切除病例的30%。约75%的AGC病例为早期癌，84%无淋巴结转移。相比之下，SGC病例中只有33%为早期癌，57%有淋巴结转移。97%的AGC和75%的SGC进行了根治性切除。根治性切除的AGC患者的5年和10年累积生存率分别为85.2%和72.2%，而SGC患者的生存率分别为66.8%和55.4%。这些数据表明，与有症状的癌症患者相比，大多数无症状胃癌患者有望接受根治性切除，即有更好的临床结局。
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