Francesconi R P, Maher J T, Bynum G D, Mason J W
J Appl Physiol Respir Environ Exerc Physiol. 1977 Aug;43(2):308-11. doi: 10.1152/jappl.1977.43.2.308.
Heat acclimatization was induced in a group of healthy male test subjects by repetitive treadmill walking (5.6 km-h-1, 49 degrees/27 degrees C dry/wet bulb, 90 min-day-1, 7 days). A second group of men, paired for maximal O2 consumption and body weight, remained sedentary under identical environmental conditions. Total plasma protein increased significantly after 45 (P less than 0.05) and 90 (P less than 0.025) min of exercise on the first day of heat exposure, yet after 7 days no increments occurred. Even after heat acclimatization was achieved (day 7), plasma levels of creatine phosphokinase increased during the 90-min walk in the heat (time O vs. 90, P less than 0.025), as was also the case on day 1 (P less than 0.05). Levels of lactate dehydrogenase, glutamate-oxaloacetate transaminase, and glutamate-pyruvate transaminase were not significantly affected by exercise in the heat either before or after heat acclimatization. No correlations could be drawn between base-line enzyme levels and state of physical conditioning.
通过重复性跑步机行走（速度5.6千米/小时，干球温度49摄氏度/湿球温度27摄氏度，每天90分钟，共7天）对一组健康男性受试对象进行热适应诱导。另一组在最大耗氧量和体重方面配对的男性，在相同环境条件下保持久坐。在热暴露第一天，运动45分钟（P<0.05）和90分钟（P<0.025）后，血浆总蛋白显著增加，但7天后没有增加。即使在实现热适应后（第7天），在热环境中进行90分钟步行期间，肌酸磷酸激酶的血浆水平仍会升高（时间0与90相比，P<0.025），第1天也是如此（P<0.05）。乳酸脱氢酶、谷草转氨酶和谷丙转氨酶的水平在热适应前后，受热环境中的运动影响均不显著。基线酶水平与身体状况之间没有相关性。
