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胆管结石的治疗:经皮内镜激光碎石术的价值

Treatment of bile duct stones: value of laser lithotripsy delivered via percutaneous endoscopy.

作者信息

Brambs H J, Duda S H, Rieber A, Scheurlen M, Claussen C D

机构信息

Department of Diagnostic Radiology, Eberhard-Karls-University, Tübingen, Germany.

出版信息

Eur Radiol. 1996;6(5):734-40. doi: 10.1007/BF00187681.

Abstract

Extraction of stones from the bile ducts via standard endoscopic techniques, a percutaneous transhepatic approach, or a T-tube track can be unsuccessful. We report our preliminary experience with a combination of percutaneous cholangioscopy and dye laser lithotripsy. Flash lamp-excited dye laser (504 nm) lithotripsy delivered by percutaneous cholangioscopy (12 F) was evaluated in 13 patients with stones in the bile ducts. Conventional endoscopic treatment had not been attempted in 4 patients after hepaticojejunostomy and had failed in 3 patients after gastric bypass surgery or gastrectomy, and in 6 patients because of technical difficulties, i.e. due mainly to largeness of stones. In 12 patients a percutaneous transhepatic route was used. In 1 patient the T-tube track was used as access to the bile ducts. Laser lithotripsy resulted in successful fragmentation of stones in 12 patients (92%). The bile ducts cleared spontaneously in 2 patients only. Using additional techniques, i.e. sphincterotomy and stent insertion, the overall combined success rate for duct clearance after laser fragmentation was 100%. Four patients had a retrograde endoscopic sphincterotomy after failed attempts for stone removal at endoscopic retrograde cholangioscopy. Two patients had an antegrade fluoroscopically monitored sphincterotomy. Bleeding complications occurred in 2 patients. This accounted for a high rate (15%) of severe complications. The intrahepatic bleeding in 1 patient was due to an intrahepatic vessel injury by the 13-F sheath. The periampullary bleeding in the other patient occurred after an antegrade papillotomy. Pulsed dye laser lithotripsy proved to be an effective technique in patients with difficult bile duct stones. The main problem of a per cutaneous approach is the complete removal of the fragmented stones, which requires additional procedures in most cases. The percutaneous access is time-consuming and bears a relatively high risk of major bleeding complications. It should therefore be restricted to cases in which conventional endoscopic procedures are impossible or unsuccessful.

摘要

通过标准内镜技术、经皮经肝途径或T管窦道从胆管取石可能不成功。我们报告了经皮胆道镜检查和染料激光碎石术联合应用的初步经验。对13例胆管结石患者进行了经皮胆道镜(12F)下闪光灯激发染料激光(504nm)碎石术评估。4例肝空肠吻合术后患者未尝试过传统内镜治疗,3例胃旁路手术或胃切除术后患者以及6例因技术困难(主要是结石较大)而治疗失败的患者也接受了该评估。12例患者采用经皮经肝途径,1例患者利用T管窦道进入胆管。激光碎石术使12例患者(92%)的结石成功破碎。仅2例患者的胆管自行通畅。通过采用额外的技术,即括约肌切开术和支架置入术,激光碎石术后胆管清除的总体联合成功率为100%。4例患者在内镜逆行胰胆管造影取石失败后接受了逆行内镜括约肌切开术。2例患者接受了顺行荧光透视监测下的括约肌切开术。2例患者出现出血并发症。这导致严重并发症的发生率较高(15%)。1例患者的肝内出血是由于13F鞘管损伤肝内血管所致。另1例患者的壶腹周围出血发生在顺行乳头切开术后。脉冲染料激光碎石术被证明是治疗困难胆管结石患者的有效技术。经皮途径的主要问题是完全清除破碎的结石,在大多数情况下这需要额外的操作。经皮入路耗时且存在相对较高的大出血并发症风险。因此,它应仅限于传统内镜手术不可能或不成功的病例。

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