Stacul F, Thomsen H S
Department of Radiology, University Hospital of Trieste, Ospedale di Cattinara, Italy.
Eur Radiol. 1996;6(5):756-61. doi: 10.1007/BF00187685.
The 10-year-long debate regarding high-os-molar ionic vs low-osmolar nonionic contrast media has ceased. Now we are confronted with at least eight nonionic monomers and two nonionic dimers. Do these ten contrast agents differ from each other? The manufacturers say yes, but in clinical practice differences have, with a few exceptions, turned out to be very marginal and by no means to the extent which was found between high- and low-osmolar contrast media. Only time will tell whether there are any major differences of clinical importance between the "old" and the new nonionic agents.
关于高渗离子型与低渗非离子型造影剂长达十年的争论已经停止。现在我们面临着至少八种非离子单体和两种非离子二聚体。这十种造影剂彼此不同吗？制造商们说是的，但在临床实践中，除了少数例外，差异非常微小，远不及高渗和低渗造影剂之间的差异程度。只有时间才能证明“旧的”和新的非离子型造影剂之间是否存在任何具有临床重要性的重大差异。
