Childers M, Reader A, Nist R, Beck M, Meyers W J
Department of Endodontics/Diagnostic Services, College of Dentistry, Ohio State University, Columbus 43210, USA.
J Endod. 1996 Jun;22(6):317-20. doi: 10.1016/S0099-2399(96)80267-6.
The purpose of this study was to determine the contribution of the periodontal ligament injection (PDL) to the inferior aveolar nerve (IAN) block in human first molars. Using a repeated-measures design, 40 subjects randomly received a combination IAN block and PDL injections of the first molar using 2% lidocaine with 1:100,000 epinephrine and a combination IAN block and mock PDL injections (needle penetration only) at two successive appointments. The first molar and adjacent teeth, and contralateral canine (positive and negative controls) were blindly tested with an Analytic Technology pulp tester at 2-min cycles for 60 min. Profound anesthesia was defined as no subject response at an 80 reading. One hundred percent of the subjects had lip numbness with the IAN block. When the combination IAN/PDL injections were compared with the IAN block, the incidence of successful pulpal anesthesia (80 reading) was significantly greater for the combination injections through the first 23 min of pulp testing. However, after 23 min, there was no increase in anesthetic success by adding the PDL to the IAN injection. We concluded that adding the PDL injection to an IAN block increased the incidence of pulpal anesthesia for the first 23 min in the first molar.
本研究的目的是确定牙周膜注射（PDL）对人类第一磨牙下牙槽神经（IAN）阻滞的作用。采用重复测量设计，40名受试者在两次连续就诊时，随机接受使用含1:100,000肾上腺素的2%利多卡因对第一磨牙进行IAN阻滞联合PDL注射，以及IAN阻滞联合模拟PDL注射（仅针头穿刺）。使用Analytic Technology牙髓活力测试仪在2分钟周期内对第一磨牙及相邻牙齿和对侧尖牙（阳性和阴性对照）进行60分钟的盲法测试。深度麻醉定义为在读数为80时无受试者反应。100%的受试者在IAN阻滞时出现唇部麻木。当将IAN/PDL联合注射与IAN阻滞进行比较时，在牙髓测试的前23分钟内，联合注射的牙髓麻醉成功发生率（读数为80）显著更高。然而，23分钟后，在IAN注射中添加PDL并没有增加麻醉成功率。我们得出结论，在IAN阻滞中添加PDL注射可提高第一磨牙在前23分钟内的牙髓麻醉发生率。
