Kazak A E, Penati B, Boyer B A, Himelstein B, Brophy P, Waibel M K, Blackall G F, Daller R, Johnson K
Children's Hospital of Philadelphia, Division of Oncology, Pennsylvania 19104-4399, USA.
J Pediatr Psychol. 1996 Oct;21(5):615-31. doi: 10.1093/jpepsy/21.5.615.
Evaluated distress during invasive procedures in childhood leukemia. Child and parent distress, assessed by questionnaires and ratings, were compared in two arms of a randomized, controlled prospective study, one a pharmacologic only (PO) (n = 45) and the other a combined pharmacologic and psychological intervention (Cl) (n = 47), at 1, 2, and 6 months after diagnosis. The cross-sectional control group (CC) consisted of parents of 70 patients in first remission prior to the prospective study. Mothers' and nurses' ratings of child distress indicated less child distress in the Cl group than the PO. When contrasted with the CC group, the Cl group showed lower levels of child distress. Data showed decreases over time in distress and concurrent improvements in quality of life and parenting stress and supported an inverse association between distress and child age.
评估儿童白血病侵入性治疗过程中的痛苦程度。在一项随机对照前瞻性研究的两个组中，通过问卷调查和评分评估儿童及其父母的痛苦程度，一组仅采用药物治疗（PO组，n = 45），另一组采用药物与心理干预相结合的治疗（Cl组，n = 47），在诊断后的1个月、2个月和6个月进行评估。横断面对照组（CC组）由前瞻性研究前处于首次缓解期的70名患者的父母组成。母亲和护士对儿童痛苦程度的评分显示，Cl组的儿童痛苦程度低于PO组。与CC组相比，Cl组的儿童痛苦程度较低。数据显示，痛苦程度随时间下降，同时生活质量和育儿压力得到改善，且支持痛苦程度与儿童年龄之间呈负相关。
