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一项针对社交恐惧症成年患者子女的高风险试点研究。

A high-risk pilot study of the children of adults with social phobia.

作者信息

Mancini C, van Ameringen M, Szatmari P, Fugere C, Boyle M

机构信息

Department of Psychiatry, McMaster University, Hamilton, Ontario, Canada.

出版信息

J Am Acad Child Adolesc Psychiatry. 1996 Nov;35(11):1511-7. doi: 10.1097/00004583-199611000-00020.

Abstract

OBJECTIVE

Children of patients with social phobia were studied to estimate their rates of psychiatric disorder.

METHOD

Twenty-six social-phobic outpatients who had at least one child between the ages of 4 and 18 years participated in the study. Information was collected from parents on all 47 children and from the children between 12 and 18 years of age. Diagnoses in the children were made based on DSM-III-R and were done by a best-estimate method, using parent and child reports from a modified Anxiety Disorders Interview Schedule for Children, the Survey Diagnostic Instrument, the Current Self-Report Childhood Inhibition Scale, and the Alcohol Dependence Survey.

RESULTS

Of the 47 children, 49% had at least one lifetime anxiety disorder diagnosis. The most common diagnoses were overanxious disorder (30%), social phobia (23%), and separation anxiety disorder (19%). Sixty-five percent had more than one anxiety disorder diagnosis. Lifetime major depression was found, in 8.5% of the children. Parents whose children met criteria for an anxiety disorder had a greater mean number of comorbid diagnoses than did the parents of unaffected children.

CONCLUSION

This pilot study suggests that children of social-phobic parents may have increased rates of psychiatric disorder. Further studies incorporating a control group are needed.

摘要

目的

对社交恐惧症患者的子女进行研究,以评估他们患精神疾病的几率。

方法

26名患有社交恐惧症的门诊患者参与了该研究,他们至少有一个年龄在4至18岁之间的孩子。研究收集了所有47名孩子家长的信息以及年龄在12至18岁之间孩子的信息。基于《精神疾病诊断与统计手册》第三版修订本(DSM-III-R)对孩子进行诊断,采用最佳估计法,依据改良版儿童焦虑症访谈量表、调查诊断工具、当前儿童自我报告抑制量表以及酒精依赖调查中的家长和孩子报告进行诊断。

结果

在这47名孩子中,49%至少有过一次终生焦虑症诊断。最常见的诊断是过度焦虑症(30%)、社交恐惧症(23%)和分离焦虑症(19%)。65%的孩子有不止一种焦虑症诊断。8.5%的孩子被诊断为终生重度抑郁症。孩子符合焦虑症标准的家长,其共病诊断的平均数量比未受影响孩子的家长更多。

结论

这项初步研究表明,社交恐惧症患者的子女患精神疾病的几率可能更高。需要进一步开展纳入对照组的研究。

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