密苏里州女性的禽类接触与肺癌风险：基于人群的病例对照研究。
Avian exposure and risk of lung cancer in women in Missouri: population based case-control study.
作者信息
Alavanja M C, Brownson R C, Berger E, Lubin J, Modigh C
机构信息
Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockvilie, MD 20852, USA.
出版信息
BMJ. 1996 Nov 16;313(7067):1233-5. doi: 10.1136/bmj.313.7067.1233.
OBJECTIVE
To investigate the association, previously reported in three European studies, between ownership of pet birds and the risk of lung cancer.
DESIGN
A population based case-control study with a structured questionnaire administered by telephone.
SETTING
Missouri, a midwestern state in the United States with a population of about 5 million.
SUBJECTS
All newly diagnosed cases of primary lung cancer in women aged 30-84 years in Missouri from 1 January 1993 to 31 January 1994 reported to the state cancer registry were invited to participate (n = 652); and 629 population based controls.
MAIN OUTCOME MEASURES
Odds ratios were computed in relation to whether or not the study subject ever kept pet birds, the type of bird kept, and several measures of intensity or duration of exposure. Odds ratios were adjusted for smoking.
RESULTS
The odds ratio (95% confidence interval) for the development of lung cancer associated with keeping pet birds was 0.84 (0.65 to 1.09). The results were similar for the type of pet bird kept, the number of birds kept, the location of the bird in the house, and the duration of ownership.
CONCLUSION
The keeping of pet birds carries no excess risk for the development of lung cancer.
目的
调查此前三项欧洲研究报告的宠物鸟饲养与肺癌风险之间的关联。
设计
一项基于人群的病例对照研究，通过电话进行结构化问卷调查。
地点
密苏里州，美国中西部的一个州，人口约500万。
研究对象
邀请了1993年1月1日至1994年1月31日向该州癌症登记处报告的密苏里州30 - 84岁女性中所有新诊断的原发性肺癌病例参与研究（n = 652）；以及629名基于人群的对照。
主要观察指标
计算与研究对象是否饲养过宠物鸟、所饲养鸟的类型以及接触强度或持续时间的几种测量指标相关的比值比。比值比针对吸烟情况进行了调整。
结果
与饲养宠物鸟相关的肺癌发生比值比（95%置信区间）为0.84（0.65至1.09）。所饲养宠物鸟的类型、饲养鸟的数量、鸟在房屋中的位置以及饲养时间长短的结果相似。
结论
饲养宠物鸟不会增加患肺癌的额外风险。
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