Holst P A, Kromhout D, Brand R
University of Leiden, The Netherlands.
BMJ. 1988 Nov 19;297(6659):1319-21. doi: 10.1136/bmj.297.6659.1319.
To find out whether keeping birds in the home is an independent risk factor for lung cancer a case-control study was carried out in four main hospitals in The Hague, The Netherlands. Forty nine patients under 65 years of age with lung cancer each were matched for age and sex with two control subjects who attended the same general practice. Data were collected on social class, cigarette smoking, intake of beta carotene and vitamin C, and alcohol consumption. It was found that smoking, birdkeeping, and a low intake of vitamin C were significantly and independently related to the incidence of lung cancer. The odds ratio for lung cancer among people who keep birds as pets was estimated to be 6.7 after adjusting for smoking and vitamin C intake. The results of this study suggest that keeping pet birds is an independent risk factor for lung cancer.
为了确定在家中饲养鸟类是否是肺癌的一个独立危险因素,在荷兰海牙的四家主要医院开展了一项病例对照研究。49名65岁以下的肺癌患者,年龄和性别分别与两名在同一家全科诊所就诊的对照者进行匹配。收集了社会阶层、吸烟、β-胡萝卜素和维生素C摄入量以及饮酒情况的数据。结果发现,吸烟、养鸟和维生素C摄入量低与肺癌发病率显著且独立相关。在对吸烟和维生素C摄入量进行调整后,将鸟类作为宠物饲养的人群患肺癌的优势比估计为6.7。这项研究的结果表明,饲养宠物鸟是肺癌的一个独立危险因素。