Orsulic S, Peifer M
Max-Planck Institüt für Immunbiologie, Freiberg, Germany.
Curr Biol. 1996 Nov 1;6(11):1363-7. doi: 10.1016/s0960-9822(96)00731-2.
A novel class of receptor-the Frizzled family-has been identified and the members shown to be receptors for Wingless and its homologs, the Wnts, which mediate key cell-cell interactions during the development of fruitflies and vertebrates, respectively.
一类新的受体——卷曲蛋白家族——已被鉴定出来,其成员被证明是无翅蛋白及其同源物Wnts的受体,它们分别在果蝇和脊椎动物发育过程中介导关键的细胞间相互作用。