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华盛顿州的隐孢子虫病:一次与井水相关的疫情爆发。

Cryptosporidiosis in Washington State: an outbreak associated with well water.

作者信息

Dworkin M S, Goldman D P, Wells T G, Kobayashi J M, Herwaldt B L

机构信息

Centers for Disease Control and Prevention, Epidemiology Program Office (Division of Field Epidemiology), Atlanta, Georgia, USA.

出版信息

J Infect Dis. 1996 Dec;174(6):1372-6. doi: 10.1093/infdis/174.6.1372.

Abstract

In 1994, an outbreak of cryptosporidiosis occurred in a rural community in Washington State where water was supplied by two deep unchlorinated wells. Confirmed case-patients had a stool specimen containing Cryptosporidium parvum oocysts. Probable case-patients had diarrhea lasting > or = 5 days. Sixty-two households (68.1% of 91) responded to a survey. Eighty-six cases (15 confirmed, 71 probable) were identified, for an attack rate of 50.9% (86/169 residents). Drinking unboiled well water was associated with being a case-patient (relative risk, 1.84; 95% confidence interval, 0.89-3.82), and a significant dose-response relationship was found between water consumption and illness (P = .004). Water that was presumed to be treated wastewater from a piped irrigation system was found dripping along one well's outer casing, which was extensively rusted. Presumptive Cryptosporidium oocysts were found in well water and in treated wastewater. This investigation demonstrates that even underground water systems are vulnerable to contamination.

摘要

1994年,华盛顿州一个农村社区爆发了隐孢子虫病,该社区的水源由两口未加氯的深水井提供。确诊病例的粪便样本中含有微小隐孢子虫卵囊。疑似病例腹泻持续时间≥5天。91户家庭中有62户(68.1%)回应了一项调查。共确认86例病例(15例确诊,71例疑似),罹患率为50.9%(86/169名居民)。饮用未煮沸的井水与成为病例有关(相对危险度,1.84;95%可信区间,0.89 - 3.82),并且发现饮水量与疾病之间存在显著的剂量反应关系(P = .004)。据推测,来自管道灌溉系统的经处理废水沿着一口井的外壳滴漏,该外壳已严重生锈。在井水中和经处理的废水中发现了推定的隐孢子虫卵囊。本次调查表明,即使是地下水系统也容易受到污染。

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