Dykes P J, Marks R
J Invest Dermatol. 1977 Sep;69(3):275-8. doi: 10.1111/1523-1747.ep12507488.
Two in vivo techniques which are rapid, inexpensive, and reproducible have been investigated. The first is a standardized radiological (xerographic) technique which we have shown is capable of detecting small degrees of dermal atrophy after the application of topical corticosteroid preparations for only one month. The second technique employs the Harpenden Skinfold Caliper used in an unconventional manner so as to exclude subcutaneous fat. We have shown that this too is capable of detecting dermal atrophy from the application of topical corticosteroids and that there is a strong correlation between the two techniques (r = 0.82, p less than 0.001). Histometric techniques, on the other hand, give inaccurate and erroneous results for dermal thickness.
已经对两种快速、廉价且可重复的体内技术进行了研究。第一种是标准化放射学（静电复印）技术，我们已经证明，在仅使用外用皮质类固醇制剂一个月后，该技术能够检测到轻微程度的皮肤萎缩。第二种技术以一种非常规方式使用哈彭登皮肤褶厚度仪，以排除皮下脂肪。我们已经证明，这一技术也能够检测外用皮质类固醇引起的皮肤萎缩，并且这两种技术之间存在很强的相关性（r = 0.82，p小于0.001）。另一方面，组织测量技术得出的皮肤厚度结果不准确且有误。
