Riviere G R, Smith K S, Carranza N, Tzagaroulaki E, Kay S L, Dock M, Zhu X, DeRouen T A
Department of Pediatric Dentistry, School of Dentistry, Oregon Health Sciences University, Portland 97201-3097, USA.
Oral Microbiol Immunol. 1996 Jun;11(3):150-5. doi: 10.1111/j.1399-302x.1996.tb00350.x.
Colonization and/or proliferation of Treponema denticola may depend on the presence of Porphyromonas gingivalis. The aims of this study were to confirm this synergistic relationship, to determine whether other oral bacteria were similarly associated with P. gingivalis and to relate coinfection to the periodontal status of plaque donors. Subgingival plaque was collected from every tooth except third molars in 106 subjects who were grouped by their worst periodontal condition. In addition to P. gingivalis, monoclonal antibodies were used to identify Campylobacter rectus, Eikenella corrodens, T. denticola, Treponema socranskii and pathogen-related oral spirochetes. Associations of these bacteria with coinfection by P. gingivalis were assessed by estimated odds ratios. The results indicate that coinfection with P. gingivalis is linked to all tested bacteria, but each pair was associated with distinct periodontal conditions. The distribution of coinfected sites suggests biased colonization of facial surfaces over lingual surfaces.
齿垢密螺旋体的定植和/或增殖可能取决于牙龈卟啉单胞菌的存在。本研究的目的是证实这种协同关系，确定其他口腔细菌是否与牙龈卟啉单胞菌存在类似关联，并将共感染与菌斑提供者的牙周状况相关联。从106名受试者除第三磨牙外的每颗牙齿采集龈下菌斑，这些受试者根据其最严重的牙周状况进行分组。除牙龈卟啉单胞菌外，还使用单克隆抗体来鉴定直肠弯曲菌、啮蚀艾肯菌、齿垢密螺旋体、索氏密螺旋体和与病原体相关的口腔螺旋体。通过估计比值比评估这些细菌与牙龈卟啉单胞菌共感染的关联。结果表明，与牙龈卟啉单胞菌的共感染与所有测试细菌有关，但每对细菌与不同的牙周状况相关。共感染部位的分布表明，面部表面的定植比舌面有偏差。
