Wicklow D T, Dowd P F, Alfatafta A A, Gloer J B
National Center for Agricultural Utilization Research, Agricultural Research Service, U.S. Department of Agriculture, Peoria, IL 61604, USA.
Can J Microbiol. 1996 Nov;42(11):1100-3. doi: 10.1139/m96-141.
Ochratoxin A, a known mycotoxin with demonstrated toxicity to insects, has been isolated from the sclerotia of the fungus Aspergillus carbonarius NRRL 369. The sclerotia, harvested from a solid substrate fermentation of corn kernels at 28 degrees C, produced quantities of ochratoxin A exceeding 50 ppm/g dry weight of sclerotia. Evidence is presented that ochratoxin A accounts for the activity of the methanol extract against larvae of the detritivorous beetle Carpophilus hemipterus (Nitidulidae) (75% reduction in feeding rate) and corn ear worm Helicoverpa zea (50% mortality with 99% reduction in weight gain among surviving larvae) when incorporated into a pinto bean diet at levels less than those occurring naturally in the sclerotia.
赭曲霉毒素A是一种已知对昆虫具有毒性的霉菌毒素，已从真菌炭黑曲霉NRRL 369的菌核中分离出来。这些菌核是在28摄氏度下对玉米粒进行固体基质发酵收获的，产生的赭曲霉毒素A含量超过50 ppm/克菌核干重。有证据表明，当以低于菌核中天然存在的水平掺入斑豆日粮中时，赭曲霉毒素A是甲醇提取物对食腐甲虫半翅锯谷盗（露尾甲科）幼虫（取食率降低75%）和玉米穗虫棉铃虫（50%死亡率，存活幼虫体重增加降低99%）具有活性的原因。
