Hiran S, Pande T K, Pani S, Vishwanathan K A
Department of Internal Medicine, J L N Hospital & Research Centre, (MP), India.
Lepr Rev. 1994 Sep;65(3):279-81. doi: 10.5935/0305-7518.19940028.
Dapsone-induced agranulocytosis is a rare adverse effect. There are various reports of agranulocytosis in patients treated with dapsone for malaria prophylaxis and other dermatological diseases. However, this adverse reaction in leprosy is not often encountered. We describe agranulocytosis in a young patient who was taking dapsone (100 mg) for borderline-tuberculoid leprosy in a rural environment.
氨苯砜引起的粒细胞缺乏症是一种罕见的不良反应。有各种关于使用氨苯砜预防疟疾和治疗其他皮肤病的患者发生粒细胞缺乏症的报告。然而,麻风病患者中这种不良反应并不常见。我们描述了一名年轻患者的粒细胞缺乏症,该患者在农村地区因边缘结核样麻风病正在服用氨苯砜(100毫克)。