Zachée P, Snauwaert J, Vandenberghe P, Hellemans L, Boogaerts M
CRUH, Clinical Research Unit Haematology, Katholieke Universiteit Leuven, Belgium.
Br J Haematol. 1996 Dec;95(3):472-81. doi: 10.1111/j.1365-2141.1996.tb08991.x.
A novel technique for the reproduction of ultramorphological images and details of the surface of normal and pathological red blood cells (RBC) was investigated. The atomic force microscope (AFM) provided high-resolution images of cell surfaces. The RBC dimensions obtained by this technique revealed differences between native red cells in smears and glutaraldehyde-fixed red cells. It was shown that fixed red blood cells were best suited for the ultramorphological imaging of the cell surface.
研究了一种用于再现正常和病理性红细胞（RBC）表面超微形态图像及细节的新技术。原子力显微镜（AFM）提供了细胞表面的高分辨率图像。通过该技术获得的红细胞尺寸揭示了涂片中原生红细胞与戊二醛固定红细胞之间的差异。结果表明，固定红细胞最适合用于细胞表面的超微形态成像。
