Dua H S, Singh A, Gomes J A, Laibson P R, Donoso L A, Tyagi S
Department of Ophthalmology, Queen's Medical Centre, University Hospital, Nottingham, UK.
Eye (Lond). 1996;10 ( Pt 4):447-50. doi: 10.1038/eye.1996.98.
The terms 'vortex keratopathy' and 'hurricane keratopathy' describe two similar conditions affecting the corneal surface. In the former, a vortex or whorl pattern is seen on the corneal surface and is due to the deposition of substances such as pigment, iron or drugs in the epithelial cells. In the latter, a similar pattern is presented by migrating epithelial cells but, unlike the former, the pattern is rendered more visible by fluorescein staining. Both represent the migratory pattern of normal epithelial cells which is otherwise not visible due to the slow rate of epithelial turnover and migration. The whorl pattern has a clockwise predisposition in the majority of cases and is hypothesised to be due to the influence of ocular electro-magnetic fields on the migrating epithelial cells. In this study we tested in vitro the effect of static magnetic fields on corneal epithelial cells. We were able to reproduce dramatic vortex or whorl patterns in response to magnetic fields, but without preferential migration towards the North or South Pole.
术语“涡状角膜病变”和“飓风状角膜病变”描述了两种影响角膜表面的相似病症。在前者中，角膜表面可见涡状或螺纹状图案，这是由于色素、铁或药物等物质沉积在上皮细胞中所致。在后者中，迁移的上皮细胞呈现出类似的图案，但与前者不同的是，荧光素染色使该图案更明显。两者均代表正常上皮细胞的迁移模式，否则由于上皮细胞更新和迁移速度缓慢而不可见。在大多数情况下，螺纹状图案有顺时针倾向，据推测这是由于眼电磁场对迁移上皮细胞的影响。在本研究中，我们在体外测试了静磁场对角膜上皮细胞的影响。我们能够通过磁场诱导出显著的涡状或螺纹状图案，但上皮细胞没有向北极或南极的优先迁移。
