Fukuda T, Kitada Y, Chen X M, Yang L, Miyase T
POLA R&D Laboratories, POLA Corporation, Yokohama, Japan.
Chem Pharm Bull (Tokyo). 1996 Nov;44(11):2173-6. doi: 10.1248/cpb.44.2173.
Two new monoterpene glycosides, kudingosides A and B, were isolated from Ku-Ding-Cha (Ligustrum pedunculare REHD.), together with a known monoterpene glycoside, (S)-lipedoside B-III, and three known phenylethanoid glycosides. Their structures were elucidated by spectroscopic and chemical means. Kudingosides A and B, and (S)-lipedoside B-III inhibited acyl-CoA: cholesterol acyltransferase (ACAT) with IC50 values of 2.70 x 10(-3)M, 2.88 x 10(-3)M, and 2.69 x 10(-4)M, respectively.
