Rath A M, Zhang J, Amouroux J, Chevrel J P
Service de Chirurgie géneralé et digestive, Hôpital Avicenne, Bobigny.
Chirurgie. 1996;121(4):253-65.
The best prosthetic material is one which provides the best mechanical resistance with the best biological tolerance. In order to assess the mechanical and histological properties of abdominal wall prostheses, we performed experimental tests in animal models comparing four materials: polypropylene, dacron, polyglactine 910 and a dacron-polyglactine 910 composite. One hundred thirty rabbits were used including 10 controls and 120 test animals. A medial laparotomy was closed with an antemuscular aponevrotic prosthesis in the test animals. Animals were sacrificed at one, two and three months after the operation. Abdominal wall and prosthesis samples were tested to determine resistance to pressure and extension, deformability and elasticity. Histology tests were also done to determine resistance quality and biological tolerance. Dacron was tolerated best and was less resistant than polypropylene, though resistance was satisfactory. There was no advantage with polyglactine compared with non-resorbable prostheses; its only indication would be a septic site. The composite material tested had a resistance comparable with that of dacron but was less well tolerated.
最佳的假体材料是一种能提供最佳机械抗性且具有最佳生物耐受性的材料。为了评估腹壁假体的机械和组织学特性，我们在动物模型中进行了实验测试，比较了四种材料：聚丙烯、涤纶、聚乙交酯910和涤纶 - 聚乙交酯910复合材料。共使用了130只兔子，其中包括10只对照动物和120只实验动物。在实验动物中，通过肌肉前腱膜假体关闭正中剖腹术。在术后1个月、2个月和3个月处死动物。对腹壁和假体样本进行测试，以确定抗压性、抗拉伸性、可变形性和弹性。还进行了组织学测试，以确定抗性质量和生物耐受性。涤纶的耐受性最佳，但其抗性低于聚丙烯，不过抗性也令人满意。与不可吸收的假体相比，聚乙交酯没有优势；其唯一的适用情况是感染部位。测试的复合材料的抗性与涤纶相当，但耐受性较差。
